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(5) cytochrome P450 enzymes, a group of heme monooxygenases, which catalyse the metabolism of endogenous and exogenous molecules by electron transfer through NADPH cofactor, and finally (6) endoplasmic reticulum, which generates ROS in response to misfolded proteins (De Almeida et al

Schizophrenia: While there are still a lot of unknowns about schizophrenia, researchers theorize that this psychological disorder is due to a lack of GAD1 in certain regions of the brain.[ref] This lack of GAD1 theoretically leads to an imbalance of too much glutamate (excitation) and too little GABA (inhibition)

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